BDBM172892 US9675593, 701

SMILES CCOc1ccc(c(C)c1)-n1cc(-c2cnn(C)c2)c(NCc2cccnc2)cc1=O

InChI Key InChIKey=JMKVJYCUXQYRHW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172892   

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM172892(US9675593, 701)
Affinity DataEC50: <5.00E+4nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
US Patent