BDBM173442 US9096601, 8-16

SMILES CC(C)n1c(Nc2cccc(c2)C(F)(F)F)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12

InChI Key InChIKey=WBIXSULLIITHLG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 173442   

TargetEpidermal growth factor receptor [L858R](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173442(US9096601, 8-16)
Affinity DataIC50: 1nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173442(US9096601, 8-16)
Affinity DataIC50: 3nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173442(US9096601, 8-16)
Affinity DataIC50: 12nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173442(US9096601, 8-16)
Affinity DataIC50: 1.00E+3nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent