BDBM174159 US9688669, Example 27

SMILES Fc1cccc(c1)[C@H]1OC(=O)N[C@@H]1c1cncc(c1)C#CCn1cc(Cl)cn1

InChI Key InChIKey=CEOFAAALJRUZKN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174159   

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM174159(US9688669, Example 27)
Affinity DataEC50:  48nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent