BDBM17447 1,2,3-triazole analogue, 3::5-(4-methylphenyl)-1H-1,2,3-triazole

SMILES Cc1ccc(cc1)-c1c[nH]nn1

InChI Key InChIKey=ZPCIKQLLQORQCV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17447   

LigandPNGBDBM17447(5-(4-methylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataKi:  15nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM17447(5-(4-methylphenyl)-1H-1,2,3-triazole | 1,2,3-triaz...)
Affinity DataIC50: 1.00E+6nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed