BDBM174843 US9115061, VIII

SMILES Cc1cc2c(C(=O)c3cccc4ccccc34)c(O)c(O)cc2c(O)c1-c1c(C)cc2c(C(=O)c3cccc4ccccc34)c(O)c(O)cc2c1O

InChI Key InChIKey=GBLSESKAVMAIIN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 174843   

TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

US Patent
LigandPNGBDBM174843(US9115061, VIII)
Affinity DataIC50: 160nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes) and purified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Burnham Institute For Medical Research

US Patent
LigandPNGBDBM174843(US9115061, VIII)
Affinity DataKd:  2.75E+3nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent