BDBM175040 US9688678, 12 (+-)-3-(2-ethoxy-3-pyridyl)-1-(4-methoxyphenyl)sulfonyl-3-[2-(1-methyl-4-piperidyl)-2,6-diazaspiro[3.3]heptan-6-yl]-2-oxo-indoline-5-carbonitrile

SMILES CCOc1cnc(OCC)c(c1)C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1cc(OC)ccn1)C#N)N1CC2(CN(C2)C2CCN(C)CC2)C1

InChI Key InChIKey=QBUWYQPEALRCLD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175040   

TargetVasopressin V1b receptor(Human)
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US Patent
LigandPNGBDBM175040(US9688678, 12 (+-)-3-(2-ethoxy-3-pyridyl)-1-(4-met...)
Affinity DataKi:  55nM ΔG°:  -9.90kcal/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent