BDBM175067 US9688678, 28 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1-[(5-methoxy-2-pyridyl)sulfonyl]-3-[2-[4-(oxetan-3-yl)piperazin-1-yl]-6-azaspiro[3.3]heptan-6-yl]-2-oxo-indoline-5-carbonitrile

SMILES CCOc1ccc(OC)cc1C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1ccc(OC)cn1)C#N)N1CC2(CN(C2)N2CCN(CC2)C2COC2)C1

InChI Key InChIKey=NBWQZGMLMNGGBF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175067   

TargetVasopressin V1b receptor(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM175067(US9688678, 28 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...)
Affinity DataKi:  5.5nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent