BDBM176072 US10047103, 105::US9688695, 105

SMILES CCc1sc(nc1COc1cc(OC)cc2oc(cc12)-c1cn2nc(OC)sc2n1)N1CCOCC1

InChI Key InChIKey=YIKCGURUWNKLFF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176072   

TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM176072(US9688695, 105 | US10047103, 105)
Affinity DataEC50:  0.320nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM176072(US9688695, 105 | US10047103, 105)
Affinity DataEC50:  0.320nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent