BDBM176560 US9120756, 22

SMILES C[C@@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key InChIKey=QSMNOKNPEPLVBN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 176560   

LigandPNGBDBM176560(US9120756, 22)
Affinity DataKi:  31.7nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

LigandPNGBDBM176560(US9120756, 22)
Affinity DataKi:  32nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM176560(US9120756, 22)
Affinity DataKi:  42.7nMAssay Description:The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent