BDBM17693 2-aminobenzimidazole, 18::N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phenyl}-5-{[2-(methylsulfanyl)pyrimidin-4-yl]oxy}-1H-1,3-benzodiazol-2-amine

SMILES CSc1nccc(Oc2ccc3nc(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)[nH]c3c2)n1

InChI Key InChIKey=JGMRAEWVFZTZRS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17693   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17693(2-aminobenzimidazole, 18 | N-{4-chloro-3-[(4-methy...)
Affinity DataKi:  128nM ΔG°:  -9.30kcal/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed