BDBM17751 6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2-dihydroquinolin-2-one::Quinolone, 2

SMILES Cc1cc(on1)C2=C(c3cc(ccc3NC2=O)Cl)c4ccccc4

InChI Key InChIKey=QINNOQKHPLWGBK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17751   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM17751(6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM17751(6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) was incubated with compound in reaction buffer. Control reactions were run in each plate. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed