BDBM177919 US9120797, 17::US9120797, 18

SMILES CC1Cc2c([nH]c3ccc(cc23)[N+]([O-])=O)C2(CCC(CC2)(N(C)C)c2ccccc2)O1

InChI Key InChIKey=AULHNJBHSOXPMG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 177919   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM177919(US9120797, 17 | US9120797, 18)
Affinity DataKi:  6.60nM ΔG°:  -11.2kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM177919(US9120797, 17 | US9120797, 18)
Affinity DataKi:  25nM ΔG°:  -10.4kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandPNGBDBM177919(US9120797, 17 | US9120797, 18)
Affinity DataKi:  29nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandPNGBDBM177919(US9120797, 17 | US9120797, 18)
Affinity DataKi:  70nM ΔG°:  -9.75kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent