BDBM177951 US9120797, 49

SMILES CNC1(CCC2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1

InChI Key InChIKey=AMXGKMSRYLZAEO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177951   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM177951(US9120797, 49)
Affinity DataKi:  6.80nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandPNGBDBM177951(US9120797, 49)
Affinity DataKi:  10nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent