BDBM177954 US9120797, 52

SMILES CN(C)C1(CCC2(CC1)c1sc3ccccc3c1CCS2=O)c1ccc(F)cc1

InChI Key InChIKey=FTMRGQOSQDXGTG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177954   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 177954BDBM177954(US9120797, 52)
Affinity DataKi:  58nM ΔG°:  -9.87kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 177954BDBM177954(US9120797, 52)
Affinity DataKi:  62nM ΔG°:  -9.83kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent