BDBM178000 US9120807, 12

SMILES O=C(c1cccs1)c1nc(NCc2cccnc2)nc2cc(NCc3cccnc3)sc12

InChI Key InChIKey=BXEPZMXZIXWQED-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 178000   

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 68.9nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 256nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 308nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 828nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent