BDBM178030 N-[4-[2-(2,4-Diamino-5-formyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (24a)

SMILES Nc1nc(N)c2N(C=O)C(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CCc2n1

InChI Key InChIKey=GTKKXIZKROZLPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178030   

TargetDihydrofolate reductase(Human)
Peking University

LigandPNGBDBM178030(N-[4-[2-(2,4-Diamino-5-formyl-5,6,7,8-tetrahydropy...)
Affinity DataIC50: 590nMpH: 7.5Assay Description:The recombinant human (rh) DHFR was purchased from Sigma-Aldrich (Shanghai, China). All rhDHFR enzymes were assayed spectrophotometrically in a solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed