BDBM17846 (5S)-3-(3-acetylphenyl)-N-[(2S,3S)-4-{[(5S)-3-(3-acetylphenyl)-2-oxo-1,3-oxazolidin-5-yl]-N'-{[4-(pyridin-2-yl)phenyl]methyl}formohydrazido}-3-hydroxy-1-phenylbutan-2-yl]-2-oxo-1,3-oxazolidine-5-carboxamide::(Hydroxyethyl)hydrazine Isostere-Based Compound, 40

SMILES CC(=O)c1cccc(c1)N1C[C@H](OC1=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(cc1)-c1ccccn1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)C(C)=O

InChI Key InChIKey=BEQKYIIVCGSEAQ-IWWWZYECSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17846   

TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School

LigandPNGBDBM17846((5S)-3-(3-acetylphenyl)-N-[(2S,3S)-4-{[(5S)-3-(3-a...)
Affinity DataKi:  1.09E+3nM ΔG°:  -8.26kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed