BDBM17849 3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)pyridine-2-carboxamide::CHEMBL316308::pyridine-2-carboxylic acid inhibitor, 2
SMILES CC(C)(C)C(=O)Nc1cccnc1C(=O)Nc1nccs1
InChI Key InChIKey=CAVCWRXFMNCBCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 17849
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 22°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 22°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair