BDBM17962 (2R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phenyl)-2-[(naphthalen-2-ylmethoxy)methyl]piperazine::Piperazine-based compound, 12

SMILES COc1ccccc1COCCCOc1ccc(cc1)N1CCNC[C@@H]1COCc1ccc2ccccc2c1

InChI Key InChIKey=IBKXZPJTGRVCRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17962   

TargetRenin(Human)
Pfizer

LigandPNGBDBM17962((2R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed