BDBM179651 US9676701, 22 (trans)-2-(6-(3-methoxy-4-methylphenyl)pyridin-3-yl)cyclopropanamine hydrochloride

SMILES COc1cc(ccc1C)-c1ccc(cn1)[C@H]1C[C@@H]1N

InChI Key InChIKey=HHEFXNZJJWWMDC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179651   

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179651(US9676701, 22 (trans)-2-(6-(3-methoxy-4-methylphen...)
Affinity DataKi:  550nM ΔG°:  -8.53kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179651(US9676701, 22 (trans)-2-(6-(3-methoxy-4-methylphen...)
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM179651(US9676701, 22 (trans)-2-(6-(3-methoxy-4-methylphen...)
Affinity DataKi: >1.00E+3nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent