BDBM179736 US9127005, P0L

SMILES C[C@@H](CN1CCC2(CC1)[C@H](CNC2=O)c1ccc(F)cc1)NC(=O)c1cnc2ccccc2c1

InChI Key InChIKey=VALMDDHRZJXVOR-FDDCHVKYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179736   

TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM179736(US9127005, P0L)
Affinity DataIC50:  100nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM179736(US9127005, P0L)
Affinity DataIC50:  700nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM179736(US9127005, P0L)
Affinity DataIC50:  200nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM179736(US9127005, P0L)
Affinity DataIC50:  725nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent