BDBM180420 US9133168, Example 38d::US9133168, Example 40d

SMILES FCC1Cc2ccccc2N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key InChIKey=UUVJAAZMPNSLBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 180420   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM180420(US9133168, Example 38d | US9133168, Example 40d)
Affinity DataIC50: 13nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM180420(US9133168, Example 38d | US9133168, Example 40d)
Affinity DataIC50: 15nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent