BDBM180797 US9133171, 11::US9133171, 12::US9133171, 2

SMILES COc1cc(F)ccc1-c1nc(Nc2cccc(CS(C)(=N)=O)c2)ncc1F

InChI Key InChIKey=ZALAVZQOVAVODO-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 180797   

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 5nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 7nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 15nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 95nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 106nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 248nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 470nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 540nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 1.10E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The principle of the assay is based on the hydrolysis of 4-nitrophenyl acetate by carbonic anhydrases (Pocker & Stone, Biochemistry, 1967, 6, 668), w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180797(US9133171, 11 | US9133171, 12 | US9133171, 2)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:The principle of the assay is based on the hydrolysis of 4-nitrophenyl acetate by carbonic anhydrases (Pocker & Stone, Biochemistry, 1967, 6, 668), w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent