BDBM180828 US9133171, 33::US9133171, 34::US9133171, 35

SMILES COc1cc(CS(C)(=N)=O)cc(Nc2ncc(F)c(n2)-c2ccc(F)cc2OC)c1

InChI Key InChIKey=NYJBTSYJXIHYOP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 180828   

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 5nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 6nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 6nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 150nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 190nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180828(US9133171, 35 | US9133171, 34 | US9133171, 33)
Affinity DataIC50: 210nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent