BDBM180850 US9133171, 55

SMILES CS(=N)(=O)Cc1cccc(Nc2ncc(F)c(n2)-c2ccc(F)cc2OCc2ccc(F)cc2)c1

InChI Key InChIKey=ZVYXVPZGGHYOJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180850   

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180850(US9133171, 55)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180850(US9133171, 55)
Affinity DataIC50: 5nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180850(US9133171, 55)
Affinity DataIC50: 770nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent