BDBM180862 US9133180, 3

SMILES CC1(C)CN(CCN1)c1ccc(cc1)-c1oc(nc1C(N)=O)-c1ccc(F)c2[nH]ccc12

InChI Key InChIKey=BLEFJHDCLNVQNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180862   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sareum

US Patent
LigandPNGBDBM180862(US9133180, 3)
Affinity DataIC50: 0.821nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetAurora kinase B(Human)
Sareum

US Patent
LigandPNGBDBM180862(US9133180, 3)
Affinity DataIC50: 9.36nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetAurora kinase A(Human)
Sareum

US Patent
LigandPNGBDBM180862(US9133180, 3)
Affinity DataIC50: 19.4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent