BDBM180968 US9133187, I-124

SMILES CN1CC(NC(=O)N2CCc3cnc(NC4CCOCC4)nc3C2)[C@@H](C1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=MEJDQSDKURCWPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180968   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM180968(US9133187, I-124)
Affinity DataIC50: 2.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent