BDBM181016 US9133199, I-253

SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)C3(CC3)CN(C3CCCC3)c2n1)C(=O)NN1CCCC1

InChI Key InChIKey=ZUESHYKNMGFCAY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181016   

TargetSerine/threonine-protein kinase PLK1(Human)
Cyclacel

US Patent
LigandPNGBDBM181016(US9133199, I-253)
Affinity DataKi: <10nMpH: 7.5Assay Description:CDC25C (2 ug/well) with PLKl (1 ug/well) in 20 mM Tris/HCl buffer pH 7.5, supplemented with 25 mM beta-glycerophosphate, 5 mM EGTA, 1 mM DTT and 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent