BDBM181114 US9138393, 4'-(Imidazol-1 yl) acetophenome::US9144538, 4'-(Imidazol-1yl) acetophenome

SMILES CC(=O)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=GAIQQJIMVVUTQN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 181114   

TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent
LigandPNGBDBM181114(US9138393, 4'-(Imidazol-1 yl) acetophenome | US914...)
Affinity DataIC50: 800nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent
LigandPNGBDBM181114(US9138393, 4'-(Imidazol-1 yl) acetophenome | US914...)
Affinity DataIC50: 800nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM181114(US9138393, 4'-(Imidazol-1 yl) acetophenome | US914...)
Affinity DataIC50: 8.26E+5nMAssay Description:Displacement of biotinylated H3Kac14 peptide from His6-tagged human BAZ2B expressed in Escherichia coli BL21(DE3) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed