BDBM181120 US9138393, Methyl- cholanthrene::US9144538, Methylcholanthrene

SMILES Cc1ccc2cc3c(ccc4ccccc34)c3CCc1c23

InChI Key InChIKey=PPQNQXQZIWHJRB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 181120   

TargetAryl hydrocarbon receptor(Human)
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM181120(US9138393, Methyl- cholanthrene | US9144538, Methy...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at AHR expressed in human HepG2 cells after 24 hrs by pXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent
LigandPNGBDBM181120(US9138393, Methyl- cholanthrene | US9144538, Methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent
LigandPNGBDBM181120(US9138393, Methyl- cholanthrene | US9144538, Methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent