BDBM181319 US9139568, 72

SMILES NC(=O)c1ccc(NC2CNCC2c2cccc(OC(F)(F)F)c2)c2cncnc12

InChI Key InChIKey=KEKMTFSRYLVCEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181319   

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM181319(US9139568, 72)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Patent

US Patent
LigandPNGBDBM181319(US9139568, 72)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A TTP Mosquito liquid handling instrument is used to place 125 ul of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent