BDBM18193 1-ethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 10b
SMILES CCN1CCOc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
InChI Key InChIKey=RZXFACZHKGAOSC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 18193
Affinity DataKi: 1.20nM ΔG°: -12.7kcal/mole EC50: 6.40nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nM ΔG°: -6.70kcal/molepH: 7.4 T: 2°CAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 8.10E+3nM ΔG°: -6.45kcal/molepH: 7.4 T: 2°CAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair