BDBM18271 (2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(carbamoylmethoxy)phenyl]methyl}-4-hydroxy-2,8-dimethylnonanamide::8-phenyl-octanecarboxamide peptidomimetic, 1

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)C[C@H](Cc1ccc(c(OCC(N)=O)c1)C(C)(C)C)C(C)C

InChI Key InChIKey=PJHHGAVXRVNVSH-NMTNEYKDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18271   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18271((2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(...)
Affinity DataIC50:  20nMpH: 7.2Assay Description:In vitro binding affinity for human renin at pH 7.2More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18271((2R,4S,5S,7S)-5-amino-N-butyl-7-{[4-tert-butyl-3-(...)
Affinity DataIC50:  20nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed