BDBM182871 US9676732, 5 3-[2-Chloro-4-(2-phenylethynyl)phenyl]-1,7-dimethyl-quinazoline-2,4-dione

SMILES Cc1ccc2c(c1)n(C)c(=O)n(-c1ccc(cc1Cl)C#Cc1ccccc1)c2=O

InChI Key InChIKey=BYQALYAQTODCTI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182871   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM182871(US9676732, 5 3-[2-Chloro-4-(2-phenylethynyl)phenyl...)
Affinity DataEC50:  93nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent