BDBM182894 US9676732, 28 3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]phenyl]-1,7-dimethyl-thieno[3,2-d]pyrimidine-2,4-dione

SMILES Cc1csc2c1n(C)c(=O)n(-c1c(F)cc(cc1F)C#Cc1cccnc1)c2=O

InChI Key InChIKey=ITPNKBNUEGONAA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182894   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM182894(US9676732, 28 3-[2,6-Difluoro-4-[2-(3-pyridyl)ethy...)
Affinity DataEC50:  29nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent