BDBM182895 US9676732, 29 2-(2,6-Difluoro-4-(phenylethynyl)phenyl)-5,6-dihydro-1H-pyrrolo[3,2,1-ij]quinazoline-1,3(2H)-dione

SMILES Fc1cc(cc(F)c1-n1c(=O)n2CCc3cccc(c23)c1=O)C#Cc1ccccc1

InChI Key InChIKey=ZINNBCHRLHPMLY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182895   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM182895(US9676732, 29 2-(2,6-Difluoro-4-(phenylethynyl)phe...)
Affinity DataEC50:  52nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent