BDBM182911 US9676732, 45 3-[3-Chloro-5-(2-phenylethynyl)-2-pyridyl]-1-isopropyl-quinazoline-2,4-dione

SMILES CC(C)n1c2ccccc2c(=O)n(-c2ncc(cc2Cl)C#Cc2ccccc2)c1=O

InChI Key InChIKey=QLEGIGNLNGOPFM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182911   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM182911(US9676732, 45 3-[3-Chloro-5-(2-phenylethynyl)-2-py...)
Affinity DataEC50:  137nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent