BDBM182922 US9676732, 56 6-[3-Fluoro-5-(2-phenylethynyl)-2-pyridyl]-4-isopropyl-2-methyl-pyrazolo[4,3-d]pyrimidine-5,7-dione

SMILES CC(C)n1c2cn(C)nc2c(=O)n(-c2ncc(cc2F)C#Cc2ccccc2)c1=O

InChI Key InChIKey=WVIJILXYSRYBOH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182922   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM182922(US9676732, 56 6-[3-Fluoro-5-(2-phenylethynyl)-2-py...)
Affinity DataEC50:  121nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent