BDBM183506 US9145354, 125::US9145354, 126::US9145354, 127

SMILES CCC(NC1CCCC1C(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F

InChI Key InChIKey=VSMFDIXNFAMVBW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183506   

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM183506(US9145354, 126 | US9145354, 127 | US9145354, 125)
Affinity DataIC50: 120nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM183506(US9145354, 126 | US9145354, 127 | US9145354, 125)
Affinity DataIC50: 290nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM183506(US9145354, 126 | US9145354, 127 | US9145354, 125)
Affinity DataIC50: 1.60E+3nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent