BDBM18367 2,5-anhydro-2,5-imino-D-glucitol based compound, 1::N-(adamantan-1-yl)-4-[(2S,3R,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]butanamide

SMILES OC[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)N1CCCC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18367   

TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute

LigandPNGBDBM18367(N-(adamantan-1-yl)-4-[(2S,3R,4R,5R)-3,4-dihydroxy-...)
Affinity DataIC50: 5.07E+5nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed