BDBM18371 N-(adamantan-1-yl)-6-[(3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-1-yl]hexanamide::isofagomine-based compound, 5

SMILES OC[C@H]1CN(CCCCCC(=O)NC23CC4CC(CC(C4)C2)C3)C[C@@H](O)[C@@H]1O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18371   

TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute

LigandPNGBDBM18371(N-(adamantan-1-yl)-6-[(3R,4R,5R)-3,4-dihydroxy-5-(...)
Affinity DataIC50: 9.40E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed