BDBM18441 4-[benzene(methyl)sulfonamido]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzamide::Sulfonamide analogue, 12

SMILES CCc1nnc(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c2ccccc2)s1

InChI Key InChIKey=MPDJPMXCUKNYCN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18441   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18441(4-[benzene(methyl)sulfonamido]-N-(5-ethyl-1,3,4-th...)
Affinity DataKi:  8.44E+3nM ΔG°:  -6.82kcal/mole IC50:  2.96E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed