BDBM186136 US9163012, 53

SMILES Cn1ccc(-c2csc([C@H]3CCCN3C(=O)OC3C4CC5CC(C4)CC3C5)n2)cc1=O

InChI Key InChIKey=VOOUNAQQLKAMAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186136   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 186136BDBM186136(US9163012, 53)
Affinity DataIC50: 0.470nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent