BDBM18634 (2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,4-difluorophenyl)-2,5-dimethylpiperazine-1-carboxamide::YM-175735

SMILES C[C@@H]1CN([C@@H](C)CN1C(=O)Nc1ccc(F)cc1F)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=WTZSNQXSDYHCRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18634   

TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18634((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 200nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18634((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human Androgen receptor measured by AR-mediated transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed