BDBM18650 (2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(methylsulfanyl)pyridin-3-yl]piperazine-1-carboxamide::N-Arylpiperazine-1-carboxamide Derivative, 27

SMILES CSc1ccc(NC(=O)N2C[C@H](C)N(C[C@H]2C)c2ccc(C#N)c(c2)C(F)(F)F)cn1

InChI Key InChIKey=UWPJPKZVJGAYBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18650   

TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18650((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 220nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed