BDBM187083 US9169209, Table 3, Compound 116

SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc(c1)C(=O)NC1CC1)\C=C\c1cccnc1

InChI Key InChIKey=ODDCILVGNOWNHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187083   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM187083(US9169209, Table 3, Compound 116)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent