BDBM18727 6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1-yloxy)ethyl]-1,2-dihydroquinoline::dihydroquinoline-based ligand, 16

SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCC=C)c2c1

InChI Key InChIKey=AHCZZOJYVQVLQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18727   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18727(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Affinity DataIC50: 116nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18727(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Affinity DataIC50: 480nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18727(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Affinity DataIC50: 970nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed