BDBM187306 US9169240, 46

SMILES COc1nc(-c2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)c(OCc2ccccc2)c(=O)[nH]1

InChI Key InChIKey=GXXDZRSGMNJIQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187306   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187306(US9169240, 46)
Affinity DataIC50: 76nMpH: 8.0Assay Description:The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent