BDBM18737 6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbut-2-en-1-yl)oxy]ethyl}-1,2-dihydroquinoline::dihydroquinoline-based ligand, 26

SMILES [#6]-[#8]-c1ccccc1-c1ccc2-[#7]C([#6])([#6])[#6]=[#6](-[#6](-[#6])-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c2c1

InChI Key InChIKey=PHKMDGYGCDKJEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18737   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18737(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbu...)
Affinity DataIC50: 395nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18737(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbu...)
Affinity DataIC50: 980nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed