BDBM18738 6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2-en-1-yloxy]ethyl}-1,2-dihydroquinoline::dihydroquinoline-based ligand, 27

SMILES CC\C=C\COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC

InChI Key InChIKey=BNKAEHGIVAYNSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18738   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18738(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2...)
Affinity DataIC50: 565nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18738(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2...)
Affinity DataIC50: 1.60E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed